CBG is a hemp-derived cannabinoid (Cannabis sativa).Like CBD, it does not make users “high.”
Although less plentiful than CBD, it has comparable therapeutic qualities.
Hemp (Cannabis sativa) contains numerous chemicals. Cannabinoids have several medicinal benefits.
THC and CBD are the major cannabinoids in hemp (cannabidiol). CBD is non-intoxicating and can be used to treat a range of medical ailments.
CBD wellness products are popular owing to their anti-inflammatory, analgesic, and antioxidant properties. CBD is one of hemp’s most abundant components, making it easier to isolate and extract for commercial use.
CBG, a non-intoxicating cannabinoid in hemp, has comparable medicinal promise. CBG can relieve inflammation, pain, and anxiety, although it’s less plentiful than CBD.
What Is CBG?
Cannabigerol, or CBG, is a hemp cannabinoid. CBG-A (acidic and inactive form) breaks down into CBD, CBG, CBC, and THC when heated.
Since CBG contains just 1% of the hemp plant, it’s hard to get enough for research. CBG maybe thousands of years old, but we know little about its composition and medical benefits.
In-vitro experiments with rats show that CBG Distillate may reduce colitis, glaucoma, and neurodegenerative symptoms.
CBG Extraction And Problems
Chromatography extracts CBG from hemp. This comprises three steps:
1. Dissolving hemp in a superfluid liquid (such as CO2 or ethanol) extracts cannabinoids.
2. This solution is evaporated under a vacuum to eliminate any gases, leaving pure CBG.
3. CBG concentrate and finished goods are maintained at room temperature and out of direct sunlight to maintain efficacy.
Given the ease of CBG’s extraction procedure and the fact that it has many medical purposes and no intoxication effects, one would wonder why it isn’t as popular as CBD.
The Expense Of Extraction Is The Key Cause
CBG is the most costly cannabinoid to extract, called the “Rolls-Royce” Why? Since hemp contains little CBG, it takes hundreds of pounds of biomass to create a little quantity.
CBG extraction requires specialized equipment. The high-performance chromatography system used to separate and purify cannabis extract must be exact to use limited raw plant material efficiently.
CBG costs growers and causes other problems. The longer a hemp plant matures, the more CBG-A and CBG break down into CBD and other cannabinoids. Cultivators can produce cannabis only for CBG or let it develop and sell it with a lesser CBG concentration.
CBG research is scarce. Studies show cannabis offers medical advantages. CBG may treat the following conditions:
- IBD And Colitis
IBS and colitis cause ulcers and inflammation in the colon and rectum.
A 2013 mouse research suggests CBG may alleviate colitis symptoms. In another trial, CBG improved stomach discomfort, cramping, hunger, diarrhea, weight loss, and nausea in IBD patients. CBG’s influence on these symptoms requires more study.
- Glaucoma, IOP
Glaucoma damages the optic nerve due to increased eye pressure (intraocular pressure).
CBG and other cannabinoids may reduce glaucoma and intraocular pressure, according to 1990 and 2008 research. CBG offers a non-intoxicating alternative to THC for managing glaucoma.
MRSA (Methicillin-Resistant Staphylococcus Aureus) is an antibiotic-resistant bacterial infection. A 2008 research found that CBG can kill drug-resistant microorganisms.
- Neurodegenerative Diseases
Huntington’s illness is progressed. It’s caused by a faulty gene that affects mobility, emotions, and cognitive skills.
A 2015 mouse research found that CBG, alone or together with other phytocannabinoids and medical therapy, might aid with neurodegenerative illnesses like Huntington’s disease. CBG normalized aberrant genes linked to brain degeneration, showing its neuroprotective potential.
- Hunger And Pain Relief
A 2016 research on rats found that CBG may help stimulate and enhance appetite in people with HIV or post-chemotherapy problems.
A 2017 research indicated that CBG can relieve pain and inflammation as an anti-oxidant.
- GABA Inhibition Re-Uptake
GABA (Gamma-aminobutyric acid) serves as a neurotransmitter in the brain. GABA uptake inhibitors diminish GABA absorption and lessen anxiety.
1975 research found that CBG blocks GABA absorption, improves muscular relaxation, and calms the brain.
- Skin Disorders
A 2007 research found that CBG improved psoriasis and eczema. Cannabinoid reduces inflammation, discomfort, and edema, according to studies.
All of the preceding studies illustrate CBG’s pharmacological therapeutic potential, but they also prove that CBG directly produces health benefits. More study is needed to properly comprehend CBG’s physiological effects.